Pediatric Immunodeficiency Disorders

Pediatric immunodeficiency disorders are a group of genetic defects characterized by abnormalities of one or more components of the immune system.

These disorders are genetically determined during infancy and childhood. The diagnosis done by the different types of tests such as differential WBC count, absolute lymphocyte count, quantitative immunoglobulin (Ig) measurements, and antibody count. Treatment usually consists of prophylactic antibiotics to manage and prevent infections.

Severe Combined Immune Deficiency (SCID) is a type of disorder found in infants that leads to life-threatening infections unless the immune system can be restored through a bone marrow transplant, enzyme replacement or gene therapy.

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